Youth and vitality

STAY HEALTHY AND CONTINUE TO THRIVE

Peptan is one of the best researched collagen peptides available on the market, whose effectiveness in supporting mobility has been scientifically proven.

Whether you are 55, 65 or 75 years old, lead an active lifestyle or simply want to enjoy your daily activities (such as walking) for as long as possible, you need healthy joints, bones, muscles, ligaments and tendons. The right supplementation can act as a preventative measure and protect you from musculoskeletal problems.

Type 1 and 2 collagen is gaining widespread recognition, thanks to a growing number of scientific research confirming its effectiveness. Peptan provides bioactive collagen peptides, with beneficial effects on connective tissue, which translates into joint support.

SCIENTIFIC RESEARCH

Discover the scientific evidence supporting the effectiveness of Peptan in supporting the maintenance of lean body mass.

• Peptan IIm for healthy joints - Peptan IIm, derived from natural raw materials, is a unique hydrolysed cartilage matrix containing bioactive type II collagen peptides, as well as chondroitin sulphate and hyaluronic acid. These components provide effective protection for cartilage against degeneration, as confirmed by scientific studies [4].
• Peptan supports healthy bones - A 2010 study [6] demonstrated that Peptan stimulates the activity of bone-forming cells while inhibiting the function of bone resorbing cells. This result is confirmed by further studies from 2012 and 2014 [7, 8].

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  Peptan helps to maintain healthy joints - In a clinical trial [5] of 94 women aged 40-70 years reporting knee joint problems, 8 g of Peptan or placebo was used daily for 6 months. In the Peptan treatment group, there was a 22% reduction in the WOMAC score, combined with a reduction in joint pain (by 32%) and an improvement in firmness (44%).
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  Collagen helps to maintain lean body mass - A double-blind crossover study [9] in a group of women aged 65-85 years compared nitrogen balance in groups using whey protein or collagen peptide supplementation. Women supplementing with whey protein lost weight and had increased nitrogen excretion, while in subjects supplementing with collagen peptides these parameters remained stable.

Bibliography:

1. Slowing down the clock with collagen peptides. White paper PEPTIDES. 2021; (January): 24–26.
2. Asserin J., Lati E., Shioya T., et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015; 14(4): 291–301. doi: 10.1111/jocd.12174. PMID: 26362110.
3. Clifford T., Ventress M., Allerton D. M., et al. The effects of collagen peptides on muscle damage, inflammation and bone turnover following exercise: a randomized, controlled trial. Amino Acids. 2019; 51(4): 691–704. doi: 10.1007/s00726-019-02706-5. PMID: 30783776.
4. Soniwala S., Scinto K. I., Schott E. M., et al. Oral hydrolyzed type 2 collagen protects against the OA of obesity and mitigates obese gut microbiome dysbiosis. Osteoarthritis and Cartilage. 2018; 26: S173–S174. doi: 10.1016/j.joca.2018.02.377.
5. Jiang J. X., Yu S., Huang Q. R., et al. Collagen peptides improve knee osteoarthritis in elderly women: A 6-month randomized, double-blind, placebo-controlled study. Agro Food Industry Hi Tech. 2014; 25(2): 19–23.
6. Guillerminet F., Beaupied H., Fabien-Soulé V., et al. Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: an in vitro and in vivo study. Bone. 2010; 46(3): 827–834. doi: 10.1016/j.bone.2009.10.035. PMID: 19895915.
7. Guillerminet F., Fabien-Soulé V., Even P. C., et al. Hydrolyzed collagen improves bone status and prevents bone loss in ovariectomized C3H/HeN mice. Osteoporos Int. 2012; 23(7): 1909–1919. doi: 10.1007/s00198-011-1788-6. PMID: 21927918.
8. Daneault A. Hydrolyzed collagen contributes to osteoblast differentiation in vitro and subsequent bone health in vivo. Osteoarthritis Cartilage. 2014; 22: S131. doi: 10.1016/j.joca.2014.02.240.
9. Hays N. P., Kim H., Wells A. M., et al. Effects of whey and fortified collagen hydrolysate protein supplements on nitrogen balance and body composition in older women. J Am Diet Assoc. 2009; 109(6): 1082–1087. doi: 10.1016/j.jada.2009.03.003. PMID: 19465192.